| Bioactivity | [D-Trp11]-Neurotensin, an analogue of Neurotensin (NT), is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can inhibit NT-induced hypotension[1][2]. |
| Invitro | [D-Trp11]-Neurotensin (0.13-1.1 μM) markedly inhibits NT-induced coronary vessel constriction in perfused rat hearts[1].[D-Trp11]-Neurotensin (2-110 μM) exhibits NT-like activity in perfused rat hearts[1]. |
| Name | [D-Trp11]-Neurotensin |
| CAS | 73634-68-1 |
| Sequence | {Pyr}-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-{D-Trp}-Ile-Leu |
| Shortening | {Pyr}-LYENKPRRP-{D-Trp}-IL |
| Formula | C80H122N22O19 |
| Molar Mass | 1695.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[D-Trp11]-Neurotensin
CAS: 73634-68-1 F: C80H122N22O19 W: 1695.96
-Neurotensin, an analogue of Neurotensin (NT), is a selective antagonist of NT in perfused rat hearts but behaves as a f
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